Feline calicivirus (FCV), ATCC VR-782 This virus is a non-enveloped, positive-stranded RNA member of the genus Vesivirus, and a common cause of respiratory infections in cats. Symptoms of infection in felines include nasal discharge and mouth ulcers.
As a member of the Caliciviridae viral family, FCV is closely related to human noroviruses, which cause acute gastroenteritis marked by nausea, vomiting, and diarrhea. Unlike human norovirus, however, a simple cell culture assay system is available for FCV. Therefore, feline calicivirus is the US EPA-approved surrogate microorganism for human norovirus label claims. Both FCV and human norovirus are able to remain viable on environmental surfaces for extended periods of time and are resistant to a number of disinfectant actives.
Permissive Host Cell Line Selected for FCV: CRFK (Crandell-Rees Feline Kidney Cells), ATCC CCL-94
